Endocannabinoid contribution to Δ9-tetrahydrocannabinol discrimination in rodents
نویسندگان
چکیده
منابع مشابه
Δ9-tetrahydrocannabinol and endocannabinoid degradative enzyme inhibitors attenuate intracranial self-stimulation in mice.
A growing body of evidence implicates endogenous cannabinoids as modulators of the mesolimbic dopamine system and motivated behavior. Paradoxically, the reinforcing effects of Δ(9)-tetrahydrocannabinol (THC), the primary psychoactive constituent of cannabis, have been difficult to detect in preclinical rodent models. In this study, we investigated the impact of THC and inhibitors of the endocan...
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ژورنال
عنوان ژورنال: European Journal of Pharmacology
سال: 2014
ISSN: 0014-2999
DOI: 10.1016/j.ejphar.2014.05.013